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F L O R I D A H O U S E O F R E P R E S E N T A T I V E S
A bill to be entitled 1
An act relating to nitazene derivatives; amending s. 2
893.03, F.S.; listing certain nitazene derivatives in 3
schedule I of the schedule of controlled substances; 4
providing an effective date. 5
6
Be It Enacted by the Legislature of the State of Florida: 7
8
Section 1. Paragraph (a) of subsection (1) of section 9
893.03, Florida Statutes, is amended to read: 10
893.03 Standards and schedules. —The substances enumerated 11
in this section are controlled by this chapter. The controlled 12
substances listed or to be listed in Schedules I, II, III, IV, 13
and V are included by whatever official, common, usual, 14
chemical, trade name, or class designated. The provisions of 15
this section shall not be construed to include within any of the 16
schedules contained in this section any excluded drugs listed 17
within the purview of 21 C.F.R. s. 1308.22, styled "Excluded 18
Substances"; 21 C.F.R. s. 1308.24, styled "Exempt Chemical 19
Preparations"; 21 C.F.R. s. 1308.32, styled "Exempted 20
Prescription Products"; or 21 C.F.R. s. 1308.34, styled "Exempt 21
Anabolic Steroid Products." 22
(1) SCHEDULE I.—A substance in Schedule I has a high 23
potential for abuse and has no currently accepted medical use in 24
treatment in the United States and in its use under medical 25
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supervision does not meet accepted safety standards. The 26
following substances are controlled in Schedule I: 27
(a) Unless specifically excepted or unle ss listed in 28
another schedule, any of the following substances, including 29
their isomers, esters, ethers, salts, and salts of isomers, 30
esters, and ethers, whenever the existence of such isomers, 31
esters, ethers, and salts is possible within the specific 32
chemical designation: 33
1. Acetyl-alpha-methylfentanyl. 34
2. Acetylmethadol. 35
3. Allylprodine. 36
4. Alphacetylmethadol (except levo -alphacetylmethadol, 37
also known as levo-alpha-acetylmethadol, levomethadyl acetate, 38
or LAAM). 39
5. Alphamethadol. 40
6. Alpha-methylfentanyl (N-[1-(alpha-methyl-betaphenyl) 41
ethyl-4-piperidyl] propionanilide; 1 -(1-methyl-2-phenylethyl)-4-42
(N-propanilido) piperidine). 43
7. Alpha-methylthiofentanyl. 44
8. Alphameprodine. 45
9. Benzethidine. 46
10. Benzylfentanyl. 47
11. Betacetylmethadol. 48
12. Beta-hydroxyfentanyl. 49
13. Beta-hydroxy-3-methylfentanyl. 50
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14. Betameprodine. 51
15. Betamethadol. 52
16. Betaprodine. 53
17. Clonitazene. 54
18. Dextromoramide. 55
19. Diampromide. 56
20. Diethylthiambutene. 57
21. Difenoxin. 58
22. Dimenoxadol. 59
23. Dimepheptanol. 60
24. Dimethylthiambutene. 61
25. Dioxaphetyl butyrate. 62
26. Dipipanone. 63
27. Ethylmethylthiambutene. 64
28. Etonitazene. 65
29. Etoxeridine. 66
30. Flunitrazepam. 67
31. Furethidine. 68
32. Hydroxypethidine. 69
33. Ketobemidone. 70
34. Levomoramide. 71
35. Levophenacylmorphan. 72
36. Desmethylprodine (1 -Methyl-4-Phenyl-4-73
Propionoxypiperidine). 74
37. 3-Methylfentanyl (N-[3-methyl-1-(2-phenylethyl)-4-75
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piperidyl]-N-phenylpropanamide). 76
38. 3-Methylthiofentanyl. 77
39. Morpheridine. 78
40. Noracymethadol. 79
41. Norlevorphanol. 80
42. Normethadone. 81
43. Norpipanone. 82
44. Para-Fluorofentanyl. 83
45. Phenadoxone. 84
46. Phenampromide. 85
47. Phenomorphan. 86
48. Phenoperidine. 87
49. PEPAP (1-(2-Phenylethyl)-4-Phenyl-4-88
Acetyloxypiperidine). 89
50. Piritramide. 90
51. Proheptazine. 91
52. Properidine. 92
53. Propiram. 93
54. Racemoramide. 94
55. Thenylfentanyl. 95
56. Thiofentanyl. 96
57. Tilidine. 97
58. Trimeperidine. 98
59. Acetylfentanyl. 99
60. Butyrylfentanyl. 100
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61. Beta-Hydroxythiofentanyl. 101
62. Fentanyl Derivatives. Un less specifically excepted, 102
listed in another schedule, or contained within a pharmaceutical 103
product approved by the United States Food and Drug 104
Administration, any material, compound, mixture, or preparation, 105
including its salts, isomers, esters, or ether s, and salts of 106
isomers, esters, or ethers, whenever the existence of such salts 107
is possible within any of the following specific chemical 108
designations containing a 4 -anilidopiperidine structure: 109
a. With or without substitution at the carbonyl of the 110
aniline moiety with alkyl, alkenyl, carboalkoxy, cycloalkyl, 111
methoxyalkyl, cyanoalkyl, or aryl groups, or furanyl, 112
dihydrofuranyl, benzyl moiety, or rings containing heteroatoms 113
sulfur, oxygen, or nitrogen; 114
b. With or without substitution at the piperidine amino 115
moiety with a phenethyl, benzyl, alkylaryl (including 116
heteroaromatics), alkyltetrazolyl ring, or an alkyl or 117
carbomethoxy group, whether or not further substituted in the 118
ring or group; 119
c. With or without substitution or addition to the 120
piperdine ring to any extent with one or more methyl, 121
carbomethoxy, methoxy, methoxymethyl, aryl, allyl, or ester 122
groups; 123
d. With or without substitution of one or more hydrogen 124
atoms for halogens, or methyl, alkyl, or methoxy groups, in the 125
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aromatic ring of the an ilide moiety; 126
e. With or without substitution at the alpha or beta 127
position of the piperidine ring with alkyl, hydroxyl, or methoxy 128
groups; 129
f. With or without substitution of the benzene ring of the 130
anilide moiety for an aromatic heterocycle; and 131
g. With or without substitution of the piperidine ring for 132
a pyrrolidine ring, perhydroazepine ring, or azepine ring; 133
excluding, Alfentanil, Carfentanil, Fentanyl, and Sufentanil; 134
including, but not limited to: 135
(I) Acetyl-alpha-methylfentanyl. 136
(II) Alpha-methylfentanyl (N-[1-(alpha-methyl-betaphenyl) 137
ethyl-4-piperidyl] propionanilide; 1 -(1-methyl-2-phenylethyl)-4-138
(N-propanilido) piperidine). 139
(III) Alpha-methylthiofentanyl. 140
(IV) Benzylfentanyl. 141
(V) Beta-hydroxyfentanyl. 142
(VI) Beta-hydroxy-3-methylfentanyl. 143
(VII) 3-Methylfentanyl (N-[3-methyl-1-(2-phenylethyl)-4-144
piperidyl]-N-phenylpropanamide). 145
(VIII) 3-Methylthiofentanyl. 146
(IX) Para-Fluorofentanyl. 147
(X) Thenylfentanyl or Thienyl fentanyl. 148
(XI) Thiofentanyl. 149
(XII) Acetylfentanyl. 150
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(XIII) Butyrylfentanyl. 151
(XIV) Beta-Hydroxythiofentanyl. 152
(XV) Lofentanil. 153
(XVI) Ocfentanil. 154
(XVII) Ohmfentanyl. 155
(XVIII) Benzodioxolefentanyl. 156
(XIX) Furanyl fentanyl. 157
(XX) Pentanoyl fentanyl. 158
(XXI) Cyclopentyl fentanyl. 159
(XXII) Isobutyryl fentanyl. 160
(XXIII) Remifentanil. 161
63. Nitazene Derivatives. Unless specifically excepted, 162
listed in another schedule, or contained within a pharmaceutical 163
product approved by the United States Food and Drug 164
Administration, any material, compound, mixture, or prepara tion, 165
including its salts, isomers, esters, or ethers, and salts of 166
isomers, esters, or ethers, whenever the existence of such salts 167
is possible within any of the following specific chemical 168
designations containing a benzimidazole ring with an ethylamine 169
substitution at the 1 -position and a benzyl ring substitution at 170
the 2-position structure: 171
a. With or without substitution on the benzimidazole ring 172
with alkyl, alkoxy, carboalkoxy, amino, nitro, aryl groups, or 173
halogens; 174
b. With or without substitution at the ethylamine amino 175
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moiety with alkyl, dialkyl, acetyl, or benzyl groups, whether or 176
not further substituted in the ring system; 177
c. With or without inclusion of the ethylamine amino 178
moiety in a cyclic structure; 179
d. With or without substitution of the benzyl ring; or 180
e. With or without replacement of the benzyl ring with an 181
aromatic ring, including, but not limited to: 182
(I) Butonitazene. 183
(II) Clonitazene. 184
(III) Etodesnitazene. 185
(IV) Etonitazene. 186
(V) Flunitazene. 187
(VI) Isotodesnitazene. 188
(VII) Isotonitazene. 189
(VIII) Metodesnitazene. 190
(IX) Metonitazene. 191
(X) Nitazene. 192
(XI) N-Desethyl Etonitazene. 193
(XII) N-Desethyl Isotonitazene. 194
(XIII) N-Piperidino Etonitazene. 195
(XIV) N-Pyrrolidino Etonitazene. 196
(XV) Protonitazene. 197
Section 2. This act shall take effect July 1, 2023. 198