S.J.R. 10 - *SJR10* SENATE JOINT RESOLUTION NO. 10–SENATORS NGUYEN, STONE; DALY, DOÑATE, FLORES, HANSEN, OHRENSCHALL AND SCHEIBLE FEBRUARY 26, 2025 ____________ JOINT SPONSORS: ASSEMBLYMEMBERS GONZÁLEZ, MOORE, NGUYEN, CARTER, WATTS; ANDERSON, BROWN-MAY, CONSIDINE, DALIA, DICKMAN, D’SILVA, GALLANT, GRAY, HANSEN, HIBBETTS, JACKSON, KARRIS, ORENTLICHER AND ROTH ____________ Referred to Committee on Legislative Operations and Elections SUMMARY—Urges Congress to take certain actions relating to the therapeutic use of certain psychedelic compounds. (BDR R-801) FISCAL NOTE: Effect on Local Government: No. Effect on the State: No. ~ EXPLANATION – Matter in bolded italics is new; matter between brackets [omitted material] is material to be omitted. SENATE JOINT RESOLUTION—Urging Congress to take certain actions relating to the therapeutic use of certain psychedelic compounds. WHEREAS, Mental health conditions, including post-traumatic 1 stress disorder (PTSD), treatment-resistant depression, anxiety 2 disorders and substance use disorders, affect millions of Americans, 3 including veterans, first responders and other residents of Nevada; 4 and 5 WHEREAS, Conventional treatments for these mental health 6 conditions often prove inadequate for many patients, leaving such 7 patients without effective therapeutic options; and 8 WHEREAS, Preliminary research has indicated that certain 9 psychedelic compounds, including psilocybin, psilocin, N,N-10 dimethyltryptamine (DMT), ibogaine, mescaline and 3,4-11 methylenedioxymethamphetamine (MDMA), when administered in 12 – 2 – - *SJR10* controlled clinical settings, show promising therapeutic potential for 1 treating various mental health conditions; and 2 WHEREAS, The United States Food and Drug Administration 3 has granted, in 2017, 2018 and 2019, respectively, MDMA-assisted 4 therapy for PTSD, psilocybin therapy for treatment-resistant 5 depression and psilocybin therapy for major depressive disorder 6 Breakthrough Therapy designation, thereby acknowledging the 7 potential of those treatments to offer substantial improvement over 8 existing treatments and expediting their development and review; 9 and 10 WHEREAS, Multiple Phase 2 and Phase 3 clinical trials have 11 demonstrated the safety and efficacy of certain psychedelic-assisted 12 therapy, with trials showing that MDMA-assisted therapy led to 67 13 percent of patients with severe PTSD no longer meeting diagnostic 14 criteria after treatment, and psilocybin-assisted therapy led to a 71-15 percent reduction in depressive symptoms at 1 week post-treatment 16 for patients with treatment-resistant depression, with 58 percent of 17 patients maintaining significant improvement at their 3-month 18 follow-up; and 19 WHEREAS, Researchers at Stanford University demonstrated 20 that ibogaine treatment led to significant improvements in veterans 21 with traumatic brain injury and PTSD, with participants 22 experiencing average reductions of 88 percent in symptoms of 23 PTSD, of 87 percent in symptoms of depression and of 81 percent in 24 symptoms of anxiety at their 1-month follow-up; and 25 WHEREAS, Multiple studies focused on veterans conducted at 26 leading institutions have shown promising results for treating PTSD 27 related to combat and traumatic brain injury with psychedelic 28 compounds, including recent breakthrough findings published in 29 Nature Medicine regarding magnesium-stabilized ibogaine for the 30 treatment of traumatic brain injury; and 31 WHEREAS, Clinical research has demonstrated significant 32 potential for psychedelic compounds to address chronic pain 33 conditions, with studies showing that the pulse administration of 34 psilocybin reduced the frequency of cluster headache attacks by 35 approximately 50 percent from baseline, from an average of 18.4 36 attacks to 9.8 attacks per week, and MDMA-assisted therapy 37 produced significant reductions in the pain intensity, disability and 38 overall pain severity of patients with PTSD with high baseline pain 39 levels; and 40 WHEREAS, The National Defense Authorization Act for Fiscal 41 Year 2024, Public Law 118-31, directed the Department of Defense 42 to establish a process for service members to participate in clinical 43 trials studying psychedelic compounds, including psilocybin and 44 MDMA, for treating PTSD and traumatic brain injury, allocated 45 – 3 – - *SJR10* $10,000,000 in funding and authorized partnerships with other 1 agencies and academic institutions, thereby demonstrating growing 2 federal recognition of the potential of these treatments; and 3 WHEREAS, The Department of Veterans Affairs has partnered 4 with researchers at Brown University and Yale University to 5 conduct a 5-year study, at the cost of $1,500,000, at the Providence 6 VA Medical Center and West Haven VA Medical Center evaluating 7 MDMA-assisted therapy for veterans with co-occurring PTSD and 8 alcohol use disorder, representing the first research initiative 9 involving psychedelic-assisted therapy funded by the Department 10 since the 1960s, and which was part of a broader effort announced 11 in January 2025 to investigate the safety and efficacy of psychedelic 12 compounds for treating veterans with mental health conditions; and 13 WHEREAS, Extensive research has demonstrated that classic 14 psychedelics have low abuse potential, with studies showing no 15 physical dependence or withdrawal symptoms and clinical evidence 16 indicating that psychedelic compounds can effectively treat 17 substance use disorders; and 18 WHEREAS, Clinical research demonstrates that psychedelic 19 compounds like psilocybin and MDMA have a favorable safety 20 profile when administered in controlled clinical settings with 21 appropriate medical screening and supervision, with studies 22 showing no lasting neuropsychological deficits, organ damage or 23 serious adverse reactions and a significantly lower rate of adverse 24 medical events compared to many current standard treatments; and 25 WHEREAS, Schedule I classification under the Controlled 26 Substances Act, 21 U.S.C. §§ 801 et seq., designates a substance as 27 having no currently accepted medical use and a high potential for 28 abuse; and 29 WHEREAS, Controlled substances classified in schedule I are 30 subject to significant barriers to research, including more 31 burdensome regulatory and bureaucratic hurdles than research of 32 other controlled substances; and 33 WHEREAS, Physicians cannot access controlled substances 34 classified in schedule I to treat patients who have terminal or life-35 threatening conditions under the Trickett Wendler, Frank Mongiello, 36 Jordan McLinn, and Matthew Bellina Right to Try Act of 2017 37 (“Right to Try Act”), Public Law 115-176, even if the controlled 38 substance is otherwise an eligible investigational drug under the 39 Act; and 40 WHEREAS, The low potential for abuse of psychedelic 41 compounds and evidence of their medical utility, particularly the 42 designation of Breakthrough Therapies by the United States Food 43 and Drug Administration, contradicts their classification as schedule 44 I controlled substances; and 45 – 4 – - *SJR10* WHEREAS, Leading medical research institutions have 1 established dedicated centers for psychedelic research, including the 2 Johns Hopkins Center for Psychedelic and Consciousness Research, 3 the Project on Psychedelics Law and Regulation at the Petrie-Flom 4 Center for Health Law Policy, Biotechnology, and Bioethics at 5 Harvard Law School, the University of California Berkeley Center 6 for the Science of Psychedelics, the New York University Langone 7 Health’s Center for Psychedelic Medicine, the Parsons Research 8 Center for Psychedelic Healing at the Icahn School of Medicine at 9 Mount Sinai, the Yale Program for Psychedelic Science, the 10 University of Wisconsin-Madison Transdisciplinary Center for 11 Research in Psychoactive Substances, the Stanford Psychedelic 12 Science Group, the Massachusetts General Hospital Center for the 13 Neuroscience of Psychedelics, the Charmaine and Gordon McGill 14 Center for Psychedelic Research and Therapy at Dell Medical 15 School at the University of Texas at Austin and the Washington 16 University Program in Psychedelics Research; and 17 WHEREAS, The State of Nevada recognizes the urgent need to 18 address the mental health crisis and expand treatment options for 19 those in need; now, therefore, be it 20 RESOLVED BY THE SENATE AND ASSEMBLY OF THE STATE OF 21 NEVADA, JOINTLY, That the Nevada Legislature hereby urges the 22 Congress of the United States and the appropriate federal agencies 23 to: 24 1. Increase federal funding for research into the therapeutic 25 applications of psychedelic compounds, particularly for treating 26 mental health conditions, substance use disorders and chronic pain; 27 2. Establish a streamlined process for approving and 28 conducting research with psychedelic compounds, while 29 maintaining appropriate safety protocols and oversight; 30 3. Establish a process to allow for compassionate medical use 31 of psychedelic eligible investigational drugs under the Right to Try 32 Act, while maintaining appropriate safety protocols and oversight; 33 4. Reschedule psilocybin, psilocin, DMT, ibogaine, mescaline 34 and MDMA to a schedule that better reflects the therapeutic value, 35 low potential for abuse and safety for use under medical supervision 36 of those compounds, giving priority to the rescheduling of 37 compounds that have received Breakthrough Therapy designation 38 from the United States Food and Drug Administration; and 39 5. Establish legal protection against federal prosecution for 40 individuals and entities complying with state law concerning the 41 supervised adult use of psychedelic compounds and require states to 42 enter research partnerships with the Attorney General under the 43 Controlled Substances Act to study the public health outcomes of 44 such state programs; and be it further 45 – 5 – - *SJR10* RESOLVED, That the Nevada Legislature supports expanded 1 research into the therapeutic potential of psychedelic compounds at 2 qualified research institutions within this State; and be it further 3 RESOLVED, That the Secretary of the Senate prepare and 4 transmit a copy of this resolution to the President of the United 5 States, the Vice President of the United States as the presiding 6 officer of the Senate, the Speaker of the House of Representatives, 7 each member of the Nevada Congressional Delegation, the 8 Administrator of the United States Drug Enforcement 9 Administration and the Director of the National Institutes of Health; 10 and be it further 11 RESOLVED, That this resolution becomes effective upon 12 passage. 13 H