Domestic Security Using Production Partnerships and Lessons from Yesterday Act of 2025 or the Domestic SUPPLY Act of 2025This bill establishes a program and sets out other requirements to promote domestic manufacturing of personal protective equipment (PPE) to address infectious diseases and other public health emergencies.Specifically, the Department of Health and Human Services (HHS) must establish a program to enter into purchasing agreements with eligible domestic manufacturers for PPE to prepare for and respond to public health emergencies. To be eligible, manufacturers must be majority owned and operated by U.S. citizens and must manufacture a majority of their contracted products domestically, with 100% of products manufactured domestically by 2028. HHS must coordinate with the Department of Defense and the Department of Homeland Security on this program.In addition, the federal government must only procure, subject to limited exceptions, clothing or equipment that is produced domestically to prevent the transmission of an infectious disease. If using federal funds, states or localities must also procure such items domestically.Further, the bill requires HHS to submit to Congress a report about changes to federal requirements for PPE since the beginning of the COVID-19 pandemic and the impact of those changes on health care workers who cared for patients in 2020 and 2021.