SENATE FLOOR VERSION - SB1216 SFLR Page 1 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 SENATE FLOOR VERSION February 22, 2024 SENATE BILL NO. 1216 By: Standridge An Act relating to the Uniform Controlled Danger ous Substances Act; amending 63 O.S. 2021, Section 2 -204, as amended by Section 1 , Chapter 120, O.S.L. 2023 (63 O.S. Supp. 2023, Section 2-204), which relates to Schedule I controlled substances; adding substances to list of Schedule I controlled substances ; updating statutory reference; and providing an effective date. BE IT ENACTED BY THE PEOPLE OF THE STATE OF OKLAHOMA: SECTION 1. AMENDATORY 63 O.S. 2021, Section 2 -204, as amended by Section 1, Chapter 120, O.S.L. 2023 (63 O.S. Supp. 2023, Section 2-204), is amended to read as follows: Section 2-204. The controlled substances listed in this section are included in Schedule I and include any material, compound, mixture or preparation that contains any quan tity of the following hallucinogenic substances, their salts, isomers and salts of isomers, unless specifically excepted, when the existence of these salts, isomers and salts of isomers is possible within the specific chemical designation. A. Any of the following opiates including their isomers, esters, ethers, salts, and salts of isomers, esters, a nd ethers, SENATE FLOOR VERSION - SB1216 SFLR Page 2 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 unless specifically excepted, when the existence of these isomers, esters, ethers, and salts is possible within the specific chemical designation: 1. Acetylmethadol; 2. Allylprodine; 3. Alphacetylmethadol; 4. Alphameprodine; 5. Alphamethadol; 6. Benzethidine; 7. Betacetylmethadol; 8. Betameprodine; 9. Betamethadol; 10. Betaprodine; 11. Clonitazene; 12. Dextromoramide; 13. Dextrorphan (except its methyl ether); 14. Diampromide; 15. Diethylthiambutene; 16. Dimenoxadol; 17. Dimepheptanol; 18. Dimethylthiambutene; 19. Dioxaphetyl butyrate; 20. Dipipanone; 21. Ethylmethylthiambutene; SENATE FLOOR VERSION - SB1216 SFLR Page 3 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 22. Etonitazene; 23. Etoxeridine; 24. Furethidine; 25. Hydroxypethidine; 26. Isotonitazene; 27. Ketobemidone; 28. Levomoramide; 29. Levophenacylmorphan; 30. Metonitazene; 31. Morpheridine; 32. N-desethyl isotonitazene; 33. N-pyrrolidino protonitazene ; 34. Noracymethadol; 34. 35. Norlevorphanol; 35. 36. Normethadone; 36. 37. Norpipanone; 37. 38. Phenadoxone; 38. 39. Phenampromide; 39. 40. Phenomorphan; 40. 41. Phenoperidine; 41. 42. Piritramide; 42. 43. Proheptazine; 43. 44. Properidine; 44. 45. Protonitazene; SENATE FLOOR VERSION - SB1216 SFLR Page 4 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 45. 46. Racemoramide; or 46. 47. Trimeperidine. B. Any of the following opium derivatives , their salts, isomers, and salts of isomers, unless specifi cally excepted, when the existence of these salts, isomers, and salts of isomers is possible within the specific chemical designation: 1. Acetorphine; 2. Acetyldihydrocodeine; 3. Benzylmorphine; 4. Codeine methylbromide; 5. Codeine-N-Oxide; 6. Cyprenorphine; 7. Desomorphine; 8. Dihydromorphine; 9. Etorphine; 10. Heroin; 11. Hydromorphinol; 12. Methyldesorphine; 13. Methylhydromorphine; 14. Morphine methylbromide; 15. Morphine methylsulfonate; 16. Morphine-N-Oxide; 17. Myrophine; 18. Nicocodeine; SENATE FLOOR VERSION - SB1216 SFLR Page 5 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 19. Nicomorphine; 20. Normorphine; 21. Phoclodine; 22. Thebacon; 23. N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-acetamide (Acetyl fentanyl); 24. N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-butenamide (Crotonyl fentanyl); 25. N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-2- furancarboxamide (Furanyl fentanyl); 26. N-phenyl-1-(2-phenylethyl)-4-piperidinamine (4-ANPP); 27. N-(1-phenethylpiperidin-4-yl)-N- phenylcyclopropanecarboxamide (Cyclopropyl fentanyl); or 28. N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-butanamide (Butyrl fentanyl). C. Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, when the ex istence of these salts, isomers, and salts of isomers is possible within the specific chemical design ation: 1. Methcathinone; 2. 3, 4-methylenedioxy amphetamine; 3. 3, 4-methylenedioxy methamphetamine; 4. 5-methoxy-3, 4-methylenedioxy amphetamine; SENATE FLOOR VERSION - SB1216 SFLR Page 6 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 5. 3, 4, 5-trimethoxy amphetamine; 6. Bufotenine; 7. Diethyltryptamine; 8. Dimethyltryptamine; 9. 4-methyl-2, 5-dimethoxyamphetamine; 10. Ibogaine; 11. Lysergic acid diethylamide; 12. Marijuana; 13. Mescaline; 14. N-benzylpiperazine; 15. N-ethyl-3-piperidyl benzilate; 16. N-methyl-3-piperidyl benzilate; 17. Psilocybin; 18. Psilocyn; 19. 2, 5 dimethoxyamphetamine; 20. 4 Bromo-2, 5-dimethoxyamphetamine; 21. 4 methoxyamphetamine; 22. Cyclohexamine; 23. Salvia Divinorum; 24. Salvinorin A; 25. Thiophene Analog of Phencyclidine. Also known as: 1-(1-(2- thienyl) cyclohexyl) piperidine; 2-Thienyl Analog of Phencyclidine; TPCP, TCP; 26. Phencyclidine (PCP); SENATE FLOOR VERSION - SB1216 SFLR Page 7 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 27. Pyrrolidine Analog for Phencyclidine . Also known as 1-(1- Phenylcyclohexyl) - Pyrrolidine, PCPy, PHP; 28. 1-(3-trifluoromethylphenyl) piperazine; 29. Flunitrazepam; 30. B-hydroxy-amphetamine; 31. B-ketoamphetamine; 32. 2,5-dimethoxy-4-nitroamphetamine; 33. 2,5-dimethoxy-4-bromophenethylamine; 34. 2,5-dimethoxy-4-chlorophenethylamine; 35. 2,5-dimethoxy-4-iodoamphetamine; 36. 2,5-dimethoxy-4-iodophenethylamine; 37. 2,5-dimethoxy-4-methylphenethylamine; 38. 2,5-dimethoxy-4-ethylphenethylamine; 39. 2,5-dimethoxy-4-fluorophenethylamine; 40. 2,5-dimethoxy-4-nitrophenethylamine; 41. 2,5-dimethoxy-4-ethylthio-phenethylamine; 42. 2,5-dimethoxy-4-isopropylthio-phenethylamine; 43. 2,5-dimethoxy-4-propylthio-phenethylamine; 44. 2,5-dimethoxy-4-cyclopropylmethylthio-phenethylamine; 45. 2,5-dimethoxy-4-tert-butylthio-phenethylamine; 46. 2,5-dimethoxy-4-(2-fluoroethylthio)-phenethylamine; 47. 5-methoxy-N, N-dimethyltryptamine; 48. N-methyltryptamine; 49. A-ethyltryptamine; SENATE FLOOR VERSION - SB1216 SFLR Page 8 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 50. A-methyltryptamine; 51. N, N-diethyltryptamine; 52. N, N-diisopropyltryptamine; 53. N, N-dipropyltryptamine; 54. 5-methoxy-a-methyltryptamine; 55. 4-hydroxy-N, N-diethyltryptamine; 56. 4-hydroxy-N, N-diisopropyltryptamine; 57. 5-methoxy-N, N-diisopropyltryptamine; 58. 4-hydroxy-N-isopropyl-N-methyltryptamine; 59. 3,4-Methylenedioxymethcathinone (Methylone); 60. 3,4-Methylenedioxypyrovalerone (MDPV); 61. 3-Methylmethcathinone (Metaphedrone); 62. 4-Methylmethcathinone (Mephedrone); 62. 63. 4-methoxymethcathinone; 63. 64. 4-Fluoromethcathinone; 64. 65. 3-Fluoromethcathinone; 65. 66. 1-(8-bromobenzo 1,2-b;4,5-b’ difuran-4-yl)-2- aminopropane; 66. 67. 2,5-Dimethoxy-4-chloroamphetamine; 67. 68. 4-Methylethcathinone; 68. 69. Pyrovalerone; 69. 70. N,N-diallyl-5-methoxytryptamine; 70. 71. 3,4-Methylenedioxy-N-ethylcathinone (Ethylone); 71. 72. B-keto-N-Methylbenzodioxolylbuta namine (Butylone); SENATE FLOOR VERSION - SB1216 SFLR Page 9 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 72. 73. B-keto-Methylbenzodioxolylpentanamine ( Pentylone); 73. 74. Alpha-Pyrrolidinopentiophenone; 74. 75. 4-Fluoroamphetamine; 75. 76. Pentedrone; 76. 77. 4’-Methyl-a-pyrrolidinohexaphenone; 77. 78. 2,5-dimethoxy-4-(n)-propylphenethylamine; 78. 79. 2,5-dimethoxyphenethylamine; 79. 80. 1,4-Dibenzylpiperazine; 80. 81. N,N-Dimethylamphetamine; 81. 82. 4-Fluoromethamphetamine; 82. 83. 4-Chloro-2,5-dimethoxy-N-(2- methoxybenzyl)phenethylamine (25C-NBOMe); 83. 84. 4-Iodo-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine (25I-NBOMe); 84. 85. 4-Bromo-2,5-dimethoxy-N-(2-methoxybenzy)phenethylamine (25B-NBOMe); 85. 86. 1-(4-Fluorophenyl)piperazine; 86. 87. Methoxetamine; 87. 88. 3,4-dichloro-N[2-dimethylamino)cyclohexyl]-N- methylbenzamide; 88. 89. N-ethyl hexadrone; 89. 90. Isopropyl-U-47700; 90. 91. Para-fluorobutyrl fentanyl; 92. Para-fluorofentanyl (pFF); SENATE FLOOR VERSION - SB1216 SFLR Page 10 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 91. 93. Fluoro isobutryrl fentanyl; 92. 94. 3-Hydroxy Phencyclidine (PCP); 93. 95. 3-methoxy Phencyclidine (PCP); 94. 96. Flualprazolam; or 95. 97. Flubromazolam. D. Unless specifically excepted or unless listed in a di fferent schedule, any material, compound, mixtur e, or preparation which contains any quantit y of the following substances having stimulant or depressant effect on the central nervous system: 1. Fenethylline; 2. Mecloqualone; 3. N-ethylamphetamine; 4. Methaqualone; 5. Gamma-Hydroxybutyric Acid, also known as GHB, gamma- hydroxybutyrate, 4-hydroxybutyrate, 4-hydroxybutanoic acid, sodium oxybate, and sodium oxybutyrate; 6. Gamma-Butyrolactone (GBL) as packaged, marketed, manufactured or promoted for human consumption, with the exception of legitimate food additive and manufacturing purposes; 7. Gamma Hydroxyvalerate (GHV) as packaged, marketed, or manufactured for human consumption, wit h the exception of legitimate food additive and manufacturing purposes ; SENATE FLOOR VERSION - SB1216 SFLR Page 11 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 8. Gamma Valerolactone (GVL) as packaged, marketed, or manufactured for human consumption , with the exception of legitimate food additive and manufacturing purposes; 9. 1,4 Butanediol (1,4 BD or BDO) as packaged, marketed, manufactured, or promoted for human consumption with the exception of legitimate manufacturing purposes; or 10. N-ethylpentylone. E. 1. The following industrial uses of Gamma-Butyrolactone, Gamma Hydroxyvalerate, Gamma Valerolactone, or 1,4 Butanediol are excluded from all schedule s of controlled substances under this title: a. pesticides, b. photochemical etching, c. electrolytes of small batteries or capacitors, d. viscosity modifiers in polyurethane, e. surface etching of metal coated plastics, f. organic paint disbursements for water soluble inks, g. pH regulators in the dyeing of wool and polyamide fibers, h. foundry chemistry as a catalyst during curing, i. curing agents in many coating systems based on urethanes and amides, j. additives and flavoring agents in food, c onfectionary, and beverage products, SENATE FLOOR VERSION - SB1216 SFLR Page 12 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 k. synthetic fiber and clothing production, l. tetrahydrofuran production, m. gamma butyrolactone production, n. polybutylene terephthalate resin production, o. polyester raw materials for polyurethane elastomers and foams, p. coating resin raw materi al, and q. as an intermediate in the manufacture of other chemicals and pharmaceuticals. 2. At the request of any person, the Director of the Oklahoma State Bureau of Narcotics and Dan gerous Drugs Control may exempt any other product containing Gamma-Butyrolactone, Gamma Hydroxyvalerate, Gamma Valerolactone, or 1,4 Butanedi ol from being included as a Schedule I controlled substance if s uch product is labeled, marketed, manufactured and distributed for legitimate industrial use in a manner that reduces or eliminates the likelihood of abuse. 3. In making a determination regar ding an industrial product, the Director, after notice and heari ng, shall consider the following: a. the history and current pattern of abuse, b. the name and labeling of the product, c. the intended manner of distribution, advertising and promotion of the product, and SENATE FLOOR VERSION - SB1216 SFLR Page 13 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 d. other factors as may be relevant to and consist ent with the public health and safety. 4. The hearing shall be held in accordance with the procedures of the Administrative Procedures Act. F. Any material, compound, mixture, or preparation , whether produced directly or indirectly from a substance of ve getable origin or independently by means of chemical synthesis, or by a combination of extraction and chemical synthesis, that contains any quantity of the following substances, or that contai ns any of their salts, isomers, and salts of isomers when the ex istence of these salts, isomers, and salts of isomers is possible within the specific chemical designation: 1. JWH-004; 2. JWH-007; 3. JWH-009; 4. JWH-015; 5. JWH-016; 6. JWH-018; 7. JWH-019; 8. JWH-020; 9. JWH-030; 10. JWH-046; 11. JWH-047; 12. JWH-048; SENATE FLOOR VERSION - SB1216 SFLR Page 14 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 13. JWH-049; 14. JWH-050; 15. JWH-070; 16. JWH-071; 17. JWH-072; 18. JWH-073; 19. JWH-076; 20. JWH-079; 21. JWH-080; 22. JWH-081; 23. JWH-082; 24. JWH-094; 25. JWH-096; 26. JWH-098; 27. JWH-116; 28. JWH-120; 29. JWH-122; 30. JWH-145; 31. JWH-146; 32. JWH-147; 33. JWH-148; 34. JWH-149; 35. JWH-150; 36. JWH-156; SENATE FLOOR VERSION - SB1216 SFLR Page 15 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 37. JWH-167; 38. JWH-175; 39. JWH-180; 40. JWH-181; 41. JWH-182; 42. JWH-184; 43. JWH-185; 44. JWH-189; 45. JWH-192; 46. JWH-193; 47. JWH-194; 48. JWH-195; 49. JWH-196; 50. JWH-197; 51. JWH-198; 52. JWH-199; 53. JWH-200; 54. JWH-201; 55. JWH-202; 56. JWH-203; 57. JWH-204; 58. JWH-205; 59. JWH-206; 60. JWH-207; SENATE FLOOR VERSION - SB1216 SFLR Page 16 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 61. JWH-208; 62. JWH-209; 63. JWH-210; 64. JWH-211; 65. JWH-212; 66. JWH-213; 67. JWH-234; 68. JWH-235; 69. JWH-236; 70. JWH-237; 71. JWH-239; 72. JWH-240; 73. JWH-241; 74. JWH-242; 75. JWH-243; 76. JWH-244; 77. JWH-245; 78. JWH-246; 79. JWH-248; 80. JWH-249; 81. JWH-250; 82. JWH-251; 83. JWH-252; 84. JWH-253; SENATE FLOOR VERSION - SB1216 SFLR Page 17 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 85. JWH-262; 86. JWH-292; 87. JWH-293; 88. JWH-302; 89. JWH-303; 90. JWH-304; 91. JWH-305; 92. JWH-306; 93. JWH-307; 94. JWH-308; 95. JWH-311; 96. JWH-312; 97. JWH-313; 98. JWH-314; 99. JWH-315; 100. JWH-316; 101. JWH-346; 102. JWH-348; 103. JWH-363; 104. JWH-364; 105. JWH-365; 106. JWH-367; 107. JWH-368; 108. JWH-369; SENATE FLOOR VERSION - SB1216 SFLR Page 18 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 109. JWH-370; 110. JWH-371; 111. JWH-373; 112. JWH-386; 113. JWH-387; 114. JWH-392; 115. JWH-394; 116. JWH-395; 117. JWH-397; 118. JWH-398; 119. JWH-399; 120. JWH-400; 121. JWH-412; 122. JWH-413; 123. JWH-414; 124. JWH-415; 125. CP-55, 940; 126. CP-47, 497; 127. HU-210; 128. HU-211; 129. WIN-55, 212-2; 130. AM-2201; 131. AM-2233; 132. JWH-018 adamantyl-carboxamide; SENATE FLOOR VERSION - SB1216 SFLR Page 19 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 133. AKB48; 134. JWH-122 N-(4-pentenyl)analog; 135. MAM2201; 136. URB597; 137. URB602; 138. URB754; 139. UR144; 140. XLR11; 141. A-796,260; 142. STS-135; 143. AB-FUBINACA; 144. AB-PINACA; 145. PB-22; 146. AKB48 N-5-Fluorpentyl; 147. AM1248; 148. FUB-PB-22; 149. ADB-FUBINACA; 150. BB-22; 151. 5-Fluoro PB-22; or 152. 5-Fluoro AKB-48. G. In addition to those substances liste d in subsection F of this section, unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or prepara tion SENATE FLOOR VERSION - SB1216 SFLR Page 20 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 which contains any quantity of a synthetic cannabinoid found to be in any of the following chemical groups: 1. Naphthoylindoles: any compound containing a 3-(1- naphthoyl)indole structure with or without substitution at the nitrogen atom of the indol e ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1 - (N-methyl-2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1 -(N-methyl- 2-pyrrolidinyl)methyl, 1 -(N-methyl-3- morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whether or not further substituted on the indole ring to any extent, and whether or not substituted on the naphthyl ring to any extent. Naphthoylindoles include, but are not limited to: a. 1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH- 200), b. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole (AM2201), c. 1-pentyl-3-(1-naphthoyl)indole (JWH-018), d. 1-butyl-3-(1-naphthoyl)indole (JWH-073), e. 1-pentyl-3-(4-methoxy-1-naphthoyl)indole (JWH-081), f. 1-propyl-2-methyl-3-(1-naphthoyl)indole (JWH-015), g. 1-hexyl-3-(1-naphthoyl)indole (JWH-019), h. 1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122), i. 1-pentyl-3-(4-ethyl-1-naphthoyl)indole (JWH-210), j. 1-pentyl-3-(4-chloro-1-naphthoyl)indole (JWH-398), SENATE FLOOR VERSION - SB1216 SFLR Page 21 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 k. 1-pentyl-2-methyl-3-(1-naphthoyl)indole (JWH-007), l. 1-pentyl-3-(7-methoxy-1-naphthoyl)indole (JWH-164), m. 1-pentyl-2-methyl-3-(4-methoxy-1-naphthoyl)indole (JWH-098), n. 1-pentyl-3-(4-fluoro-1-naphthoyl)indole (JWH-412), o. 1-[1-(N-methyl-2-piperidinyl)methyl]-3-(1- naphthoyl)indole (AM-1220), p. 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole (MAM-2201), or q. 1-(4-cyanobutyl)-3-(1-naphthoyl)indole (AM-2232); 2. Naphthylmethylindoles: any compound containing a 1H-indol-3- yl-(1-naphthyl)methane structure with or without substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halob enzyl, 1- (N-methyl-2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl- 2-pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whether or not further substituted on the indole ring to any extent, and whether or not substituted on the naphthyl ring to any extent. Naphthylmethylindoles include, but are not limited to, (1-pentylindol-3-yl)(1-naphthyl)methane (JWH-175); 3. Naphthoylpyrroles: any compound containing a 3-(1- naphthoyl)pyrrole structure with or without substitution at the nitrogen atom of the pyrrole ring by an alkyl, haloalkyl, SENATE FLOOR VERSION - SB1216 SFLR Page 22 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1-(N-methyl-2-piperidinyl)methyl, 2-(4- morpholinyl)ethyl, 1-(N-methyl-2-pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whether or not further substituted on the pyrrole ring to any extent, and whether or not substituted on the naphthyl group to any extent. Naphthoylpyrroles include, but are not limited to: a. 1-hexyl-2-phenyl-4-(1-naphthoyl)pyrrole (JWH-147), b. 1-pentyl-5-(2-methylphenyl)-3-(1-naphthoyl)pyrrole (JWH-370), c. 1-pentyl-3-(1-naphthoyl)pyrrole (JWH-030), or d. 1-hexyl-5-phenyl-3-(1-naphthoyl)pyrrole (JWH-147); 4. Naphthylideneindenes: any compound containing a 1-(1- naphthylmethylene)indene structure with or without substitution at the 3-position of the indene ring by a n alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloal kylethyl, benzyl, halobenzyl, 1-(N-methyl-2-piperidinyl)methyl, 2-(4- morpholinyl)ethyl, 1-(N-methyl-2-pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whether or not further substituted on the indene group to any extent, and whether or not substituted on the naphthyl group to any extent. Naphthylmethylindenes include, SENATE FLOOR VERSION - SB1216 SFLR Page 23 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 but are not limited to, (1-[(3-pentyl)-1H-inden-1- ylidene)methyl]naphthalene (JWH-176); 5. Phenylacetylindoles: any compound containing a 3- phenylacetylindole structure with or without substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1- (N-methyl-2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl- 2-pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whether or no t further substituted on the indole ring to any extent, and whethe r or not substituted on the phenyl ring to any extent. Phenylacetylindoles include, but are not limited to: a. 1-pentyl-3-(2-methoxyphenylacetyl)indole (JWH-250), b. 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole (RCS-8), c. 1-pentyl-3-(2-chlorophenylacetyl)indole (JWH-203), d. 1-pentyl-3-(2-methylphenylacetyl)indole (JWH-251), e. 1-pentyl-3-(4-methoxyphenylacetyl)indole (JWH-201), or f. 1-pentyl-3-(3-methoxyphenylacetyl)indole (JWH -302); 6. Cyclohexylphenols: any compound containing a 2-(3- hydroxycyclohexyl)phenol struc ture with or without substitution at the 5-position of the pheno lic ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, SENATE FLOOR VERSION - SB1216 SFLR Page 24 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 halobenzyl, 1-(N-methyl-2-piperidinyl)methyl, 2-(4- morpholinyl)ethyl, 1-(N-methyl-2-pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, (tetrahydropyran -4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, and whether or not further substituted on the cyclohexyl ring to any extent. Cyclohexylphenols include, but are not limited to: a. 5-(1,1-dimethylheptyl)-2-[(1R,3S)-3- hydroxycyclohexyl]-phenol (CP-47,497), b. 5-(1,1-dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]- phenol (cannabicyclohexanol; CP-47,497 C8 homologue), or c. 5-(1,1-dimethylheptyl)-2-[(1R,2R)-5-hydroxy-2-(3- hydroxypropyl)cyclohexyl]-phenol (CP 55, 940); 7. Benzoylindoles: any compound c ontaining a 3-(benzoyl)indole structure with or without substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, ben zyl, halobenzyl, 1-(N-methyl- 2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl-2- pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whether or not further substituted on the indole ring to any extent, and whether or not substitute d on the phenyl group to any extent. Benzoylindoles include, but are not limited to: SENATE FLOOR VERSION - SB1216 SFLR Page 25 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 a. 1-pentyl-3-(4-methoxybenzoyl)indole (RCS-4), b. 1-[2-(4-morpholinyl)ethyl]-2-methyl-3-(4- methoxybenzoyl)indole (Pravadoline or WIN 48, 098), c. 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole (AM-694), d. 1-pentyl-3-(2-iodobenzoyl)indole (AM-679), or e. 1-[1-(N-methyl-2-piperidinyl)methyl]-3-(2- iodobenzoyl)indole (AM-2233); 8. Cyclopropoylindoles: Any compound containing a 3- (cyclopropoyl)indole structure with substitutio n at the nitrogen atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1-(N-methyl- 2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl-2- pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in t he cyclopropoyl ring to any extent. Cyclopropoylindoles inclu de, but are not limited to: a. 1-pentyl-3-(2,2,3,3-tetramethylcyclopropoyl)indole (UR-144), b. 1-(5-chloropentyl)-3-(2,2,3,3- tetramethylcyclopropoyl)indole (5Cl -UR-144), or c. 1-(5-fluoropentyl)-3-(2,2,3,3- tetramethylcyclopropoyl)indole (XLR11); SENATE FLOOR VERSION - SB1216 SFLR Page 26 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 9. Indole Amides: Any compound containing a 1H-Indole-3- carboxamide structure with or without substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1 -(N-methyl- 2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl-2- pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whethe r or not substituted at the carboxamide group by an adamantyl, naphthyl, phenyl, benzyl, quinolinyl, cycloalkyl, 1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl- 1-oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- dimethyl-1-oxobutan-2-yl or pyrrole group, and whether or not further substituted in the indole, adamantyl, naphthyl, phenyl, pyrrole, quninolinyl, or cycloalkyl rings to any extent. Indole Amides include, but are not limited to: a. N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide (2NE1), b. N-(1-adamantyl)-1-(5-fluoropentyl-1H-indole-3- carboxamide (STS-135), c. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H- indole-3-carboxamide (ADBICA), d. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5- fluoropentyl)-1H-indole-3-carboxamide (5F-ADBICA), SENATE FLOOR VERSION - SB1216 SFLR Page 27 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 e. N-(naphthalen-1-yl)-1-pentyl-1H-indole-3-carboxamide (NNE1), f. 1-(5-fluoropentyl)-N-(naphthalene-1-yl)-1H-indole-3- carboxamide (5F-NNE1), g. N-benzyl-1-pentyl-1H-indole-3-carboxamide (SDB-006), or h. N-benzyl-1-(5-fluoropentyl)-1H-indole-3-carboxamide (5F-SDB-006); 10. Indole Esters: Any compound containing a 1H-Indole-3- carboxylate structure with or without substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylet hyl, benzyl, halobenzyl, 1-(N-methyl- 2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl-2- pyrrolidinyl)methyl, 1-(N-methyl-3-morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whet her or not substituted at the carboxylate group by an adamantyl, naphthy l, phenyl, benzyl, quinolinyl, cycloalkyl, 1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl- 1-oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- dimethyl-1-oxobutan-2-yl or pyrrole group, and whether or not further substituted in the in dole, adamantyl, naphthyl, phenyl, pyrrole, quinolinyl, or cycloalkyl rings to any extent. Indole Esters include, but are not limited to: SENATE FLOOR VERSION - SB1216 SFLR Page 28 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 a. quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate (PB- 22), b. quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3- carboxylate (5F-PB-22), c. quinolin-8-yl 1-(cyclohexylmethyl)-1H-indole-3- carboxylate (BB-22), d. naphthalen-1-yl 1-(4-fluorobenzyl)-1H-indole-3- carboxylate (FDU-PB-22), or e. naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3- carboxylate (NM2201); 11. Adamantanoylindoles: Any compound containing an adamantanyl-(1H-indol-3-yl)methanone structure with or without substitution at the ni trogen atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1-(N-methyl-2-piperidinyl)methyl, 2-(4- morpholinyl)ethyl, 1-(N-methyl-2-pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, whether or not further substituted in the indole ring to any extent and w hether or not substituted in the adamantyl ring to any extent. Adamantanoylindoles include, but are not limited to: a. adamantan-1-yl[1-[(1-methyl-2-piperidinyl)methyl]-1H- indol-3-yl]methanone (AM1248), or SENATE FLOOR VERSION - SB1216 SFLR Page 29 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 b. adamantan-1-yl-(1-pentyl-1H-indol-3-yl)methanone (AB- 001); 12. Carbazole Ketone: Any compound containing (9H-carbazole-3- yl) methanone structure with or without substitution at the nitrogen atom of the carbazole r ing by an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, ben zyl, halobenzyl, 1- (N-methyl-2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl- 2-pyrrolidinyl)methyl, 1-(N-methyl-3-morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, with substitution at the carbon of the methanone group by an adamantyl, naphthyl, phenyl, benzyl, quinolinyl, cycloalkyl, 1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl- 1-oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- dimethyl-1-oxobutan-2-yl or pyrrole group, and whether or not further substituted at the carbazole, adamantyl, naphthyl, phenyl, pyrrole, quinolinyl, or cycloalkyl rings to any extent. Carbazole Ketones include, but are not limited to, naphthalen-1-yl(9-pentyl- 9H-carbazol-3-yl)methanone (EG-018); 13. Benzimidazole Ketone: Any compound containing (benzimidazole-2-yl) methanone structure with or without substitution at either nitrogen atom of the benzimidazole ring b y an alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1-(N-methyl-2- piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl-2- SENATE FLOOR VERSION - SB1216 SFLR Page 30 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 pyrrolidinyl)methyl, 1-(N-methyl-3-morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or halophenyl group, with substitution at the carbon of the m ethanone group by an adamantyl, naphthyl, phenyl, benzyl, quinolinyl, cycloalkyl, 1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl- 1-oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- dimethyl-1-oxobutan-2-yl or pyrrole group, and wheth er or not further substituted in the benzimidazole, adamantyl, naphthyl, phenyl, pyrrole, quinolinyl, o r cycloalkyl rings to any extent. Benzimidazole Ketones include, but are not limited to: a. naphthalen-1-yl(1-pentyl-1H-benzo[d]imidazol-2- l)methanone (JWH-018 benzimidazole analog), or b. (1-(5-fluoropentyl)-1H-benzo[d]imidazol-2- yl)(naphthalen-1-yl)methanone (FUBIMINA); and 14. Modified by Replacement: any compound defined in this subsection that is modified by r eplacement of a carbon with nitrogen in the indole, naphthyl, indene, benzimidazole, or carbazole ring. H. Any prescription drug approved by the federal Food and Drug Administration under the pr ovisions of Section 505 of the Federal Food, Drug and Cosmetic Act, Title 21 of the United States Co de, Section 355, that is designated, rescheduled or deleted as a controlled substance under federal law by the United States Drug Enforcement Administration shall be exc luded from Schedule I and shall be prescribed, d istributed, dispensed or used in accordance SENATE FLOOR VERSION - SB1216 SFLR Page 31 (Bold face denotes Committee Amendments) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 with federal law upon the issuance of a notice, final rule or interim final rule by the United Sta tes Drug Enforcement Administration designating, rescheduling or deleting as a controlled substance such a drug product under federal law, unless and unt il the State Board of Pharmacy takes action pursuant to Section 2-201 of this title. If the Board of Pharmacy does not take action pursuant to Section 2-201 of this title, the drug product shall be deemed to be designated, rescheduled or deleted as a cont rolled substance in accordance with federal law and in compliance with the Uniform Controlled Dangerous Subst ances Act. SECTION 2. This act shall become effective November 1, 2024. COMMITTEE REPORT BY: COMMITTEE ON HEALTH AND HUMAN SERVICE S February 22, 2024 - DO PASS