IV
119THCONGRESS
1
STSESSION H. RES. 360
Expressing support for the designation of the last Tuesday of April each
year as ‘‘APOL1–Mediated Kidney Disease (AMKD) Awareness Day’’.
IN THE HOUSE OF REPRESENTATIVES
APRIL29, 2025
Ms. P
LASKETT(for herself, Ms. DELBENE, Ms. BROWNLEY, Mr. DAVISof
North Carolina, Mrs. C
HERFILUS-MCCORMICK, Ms. SEWELL, Ms.
S
TANSBURY, Ms. ADAMS, Ms. CLARKEof New York, Mr. DAVISof Illi-
nois, Ms. W
ILSONof Florida, and Mr. JOHNSONof Georgia) submitted
the following resolution; which was referred to the Committee on Energy
and Commerce
RESOLUTION
Expressing support for the designation of the last Tuesday
of April each year as ‘‘APOL1–Mediated Kidney Disease
(AMKD) Awareness Day’’.
Whereas kidney disease affects an estimated 35,500,000
Americans, and more than 550,000 are on dialysis;
Whereas Black individuals with kidney disease are more likely
to develop kidney failure than any other racial group;
Whereas the health disparities in kidney failure are
unsustainable, with Black people making up 13 percent
of the United States population but accounting for 30
percent of those with kidney failure;
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•HRES 360 IH
Whereas kidney failure places enormous physical, emotional,
and financial burdens on individuals and costs the Medi-
care Program over $45,000,000,000 annually;
Whereas there are genetic factors that can increase an indi-
vidual’s risk for kidney disease;
Whereas one such genetic factor is having variants
(mutations) in the apolipoprotein L1 (APOL1) gene;
Whereas people are more likely to have APOL1 gene variants
if they are from Western or Central Africa or have an
ancestor who came from these regions;
Whereas these variants can increase susceptibility for
APOL1-mediated kidney disease (AMKD), a rapidly pro-
gressive form of kidney disease that can lead to kidney
failure;
Whereas, it is estimated that if a patient has variants in both
copies of the APOL1 gene, there is a 1 in 5 chance they
will go on to develop kidney disease, and an estimated 13
percent of Black Americans have variants in both copies
of the APOL1 gene;
Whereas a person with AMKD may not have any symptoms
of kidney disease until their kidneys are close to failing;
Whereas genetic testing can reveal an individual’s risk for
AMKD, empowering them to take the steps necessary to
protect their kidney health before it is too late;
Whereas individuals who are found to have APOL1 genetic
variants can reduce their risk for kidney failure by meet-
ing with their doctor regularly, eating a healthy diet, tak-
ing all medications as prescribed, exercising for at least
30 minutes a day, and not smoking or using tobacco;
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•HRES 360 IH
Whereas additional awareness and research of APOL1 ge-
netic mutations are needed to improve understanding of
the kidney disease disparities in this population;
Whereas there are currently no Food and Drug Administra-
tion-approved treatments available for APOL1-mediated
kidney disease, but ongoing research and clinical trials
could provide an opportunity for researchers to develop
and test safe treatments for APOL1-mediated kidney dis-
ease; and
Whereas the House of Representatives can raise public
awareness of APOL1-mediated kidney disease: Now,
therefore, be it
Resolved, That the House of Representatives— 1
(1) expresses support for the designation of 2
‘‘APOL1-Mediated Kidney Disease (AMKD) Aware-3
ness Day’’; 4
(2) encourages each person of the United 5
States to become better informed about and aware 6
of kidney disease and APOL1-mediated kidney dis-7
ease; and 8
(3) encourages people from or with ancestry 9
from Western and Central Africa to consider genetic 10
testing for APOL1 gene mutations. 11
Æ
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