II 119THCONGRESS 1 STSESSION S. 800 To modify the Precision Medicine for Veterans Initiative of the Department of Veterans Affairs. IN THE SENATE OF THE UNITED STATES FEBRUARY27, 2025 Mr. M ORAN(for himself and Mr. KING) introduced the following bill; which was read twice and referred to the Committee on Veterans’ Affairs A BILL To modify the Precision Medicine for Veterans Initiative of the Department of Veterans Affairs. Be it enacted by the Senate and House of Representa-1 tives of the United States of America in Congress assembled, 2 SECTION 1. SHORT TITLE. 3 This Act may be cited as the ‘‘Precision Brain Health 4 Research Act of 2025’’. 5 SEC. 2. MODIFICATION OF PRECISION MEDICINE FOR VET-6 ERANS INITIATIVE. 7 Section 305 of the Commander John Scott Hannon 8 Veterans Mental Health Care Improvement Act of 2019 9 VerDate Sep 11 2014 04:49 Mar 14, 2025 Jkt 059200 PO 00000 Frm 00001 Fmt 6652 Sfmt 6201 E:\BILLS\S800.IS S800 kjohnson on DSK7ZCZBW3PROD with $$_JOB 2 •S 800 IS (38 U.S.C. 1712A note; Public Law 116–171) is amend-1 ed— 2 (1) in subsection (a), by striking ‘‘and such 3 other mental health conditions’’ and inserting ‘‘re-4 petitive low-level blast exposure, dementia, and such 5 other brain and mental health conditions’’; 6 (2) in subsection (d)(4), by adding at the end 7 the following new subparagraph: 8 ‘‘(E) D ATA-SHARING PARTNERSHIP .— 9 ‘‘(i) I N GENERAL.—The Secretary 10 shall work with the Secretary of Defense to 11 establish a data-sharing partnership be-12 tween the Department of Veterans Affairs 13 and the Department of Defense. 14 ‘‘(ii) S TORAGE.—The partnership es-15 tablished under clause (i) shall be stored in 16 the open platform made available under 17 this paragraph. 18 ‘‘(iii) D ATA.—The data supplied by 19 the Secretary of Defense shall include all 20 relevant data, Department-wide, collected 21 through— 22 ‘‘(I) the United States Armed 23 Forces; 24 VerDate Sep 11 2014 04:49 Mar 14, 2025 Jkt 059200 PO 00000 Frm 00002 Fmt 6652 Sfmt 6201 E:\BILLS\S800.IS S800 kjohnson on DSK7ZCZBW3PROD with $$_JOB 3 •S 800 IS ‘‘(II) the United States Special 1 Operations Command; and 2 ‘‘(III) the Long-Term Impact of 3 Military-Relevant Brain Injury Con-4 sortium Chronic Effects of 5 Neurotrauma Consortium maintained 6 by the Defense Health Agency.’’; and 7 (3) by adding at the end the following new sub-8 sections: 9 ‘‘(f) R EPETITIVELOW-LEVELBLASTEXPOSURERE-10 SEARCH.—In carrying out the initiative under subsection 11 (a), the Secretary of Veterans Affairs shall conduct the 12 following research: 13 ‘‘(1) A big-data assessment of the clinical and 14 non-clinical interventions that are illustrating posi-15 tive outcomes for patients within the health system 16 of the Veterans Health Administration with likely 17 low-level repetitive blast injuries, including a cat-18 egorization of military occupational specialties, and 19 units, known to experience higher levels of low-level 20 repetitive blast injuries. 21 ‘‘(2) Not fewer than two large-scale implemen-22 tation studies of research-proven interventions with-23 in such health system for patients with likely low- 24 level repetitive blast injuries, including a categoriza-25 VerDate Sep 11 2014 04:49 Mar 14, 2025 Jkt 059200 PO 00000 Frm 00003 Fmt 6652 Sfmt 6201 E:\BILLS\S800.IS S800 kjohnson on DSK7ZCZBW3PROD with $$_JOB 4 •S 800 IS tion of military occupational specialties, and units, 1 known to experience higher levels of low-level repet-2 itive blast injuries. 3 ‘‘(3) A translational research study on the use 4 of growth hormone replacement therapy on the im-5 provement of cognitive function, quality of life, brain 6 structure, and other negative symptoms on patients 7 within such health system with likely low-level repet-8 itive blast injuries. 9 ‘‘(4) Not fewer than four large-scale quality im-10 provement studies on improving the diagnosis and 11 care of veteran patients with likely low-level repet-12 itive blast injuries. 13 ‘‘(g) A SSISTANCE ANDREPORT BYNATIONALACAD-14 EMIES OFSCIENCES, ENGINEERING, ANDMEDICINE.— 15 Not later than 60 days after the date of the enactment 16 of the Precision Brain Health Research Act of 2025, the 17 Secretary of Veterans Affairs shall seek to enter into a 18 contract with the National Academies of Sciences, Engi-19 neering, and Medicine under which the National Acad-20 emies shall— 21 ‘‘(1) work in tandem with the initiative under 22 subsection (a) on validation of brain and mental 23 health biomarkers among veterans; and 24 VerDate Sep 11 2014 04:49 Mar 14, 2025 Jkt 059200 PO 00000 Frm 00004 Fmt 6652 Sfmt 6201 E:\BILLS\S800.IS S800 kjohnson on DSK7ZCZBW3PROD with $$_JOB 5 •S 800 IS ‘‘(2) not less frequently than once every two 1 years, submit to the Committee on Veterans’ Affairs 2 of the Senate and the Committee on Veterans’ Af-3 fairs of the House of Representatives a report on the 4 work completed under paragraph (1). 5 ‘‘(h) A SSESSMENT.— 6 ‘‘(1) I N GENERAL.—The Secretary of Veterans 7 Affairs shall conduct an assessment of all 8 translational research studies in progress and 9 planned under the initiative under subsection (a), in-10 cluding research under subsection (f). 11 ‘‘(2) R EPORT.—Not later than 60 days after 12 completion of the assessment conducted under para-13 graph (1), the Secretary shall submit to the Com-14 mittee on Veterans’ Affairs of the Senate and the 15 Committee on Veterans’ Affairs of the House of 16 Representatives a report on the assessment. 17 ‘‘(i) R EPORTS.— 18 ‘‘(1) I N GENERAL.—Not less frequently than 19 once every two years, the Secretary of Veterans Af-20 fairs shall submit to the Committee on Veterans’ Af-21 fairs of the Senate and the Committee on Veterans’ 22 Affairs of the House of Representatives a report on 23 the initiative under subsection (a). 24 VerDate Sep 11 2014 04:49 Mar 14, 2025 Jkt 059200 PO 00000 Frm 00005 Fmt 6652 Sfmt 6201 E:\BILLS\S800.IS S800 kjohnson on DSK7ZCZBW3PROD with $$_JOB 6 •S 800 IS ‘‘(2) RECOMMENDATIONS .—Each report re-1 quired by paragraph (1) shall include recommenda-2 tions for immediate administrative and legislative ac-3 tion to improve the initiative under subsection (a). 4 ‘‘(j) A UTHORIZATION OF APPROPRIATIONS.—There 5 is authorized to be appropriated to the Secretary of Vet-6 erans Affairs $5,000,000 to carry out the initiative under 7 subsection (a) for each of fiscal years 2025 through 8 2034.’’. 9 Æ VerDate Sep 11 2014 04:49 Mar 14, 2025 Jkt 059200 PO 00000 Frm 00006 Fmt 6652 Sfmt 6301 E:\BILLS\S800.IS S800 kjohnson on DSK7ZCZBW3PROD with $$_JOB