34 | 27 | | |
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35 | 28 | | ENGROSSED SENATE |
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36 | 29 | | BILL NO. 12 By: Standridge of the Senate |
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37 | 30 | | |
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38 | 31 | | and |
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39 | 32 | | |
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40 | 33 | | Kannady of the House |
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41 | 34 | | |
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42 | 35 | | |
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43 | 36 | | |
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44 | 37 | | |
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45 | 38 | | An Act relating to Uniform Controlled Dan gerous |
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46 | 39 | | Substances Act; amending 63 O.S. 2 011, Section 2-204, |
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47 | 40 | | as last amended by S ection 1, Chapter 207, O. S.L. |
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48 | 41 | | 2019 (63 O.S. Supp. 2020, Section 2-204), which |
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49 | 42 | | relates to Schedule I; modifying inclusions; and |
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50 | 43 | | providing an effective dat e. |
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51 | 44 | | |
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52 | 45 | | |
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53 | 46 | | |
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54 | 47 | | |
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55 | 48 | | BE IT ENACTED BY THE PEOPLE OF THE STATE OF OKLA HOMA: |
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56 | 49 | | SECTION 1. AMENDATORY 63 O.S. 201 1, Section 2-204, as |
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57 | 50 | | last amended by Section 1, Chapter 207, O.S.L. 2019 (63 O.S. Supp. |
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58 | 51 | | 2020, Section 2-204), is amended to read as follows: |
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59 | 52 | | Section 2-204. The controlled substances listed i n this section |
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60 | 53 | | are included in Schedule I and include any materia l, compound, |
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61 | 54 | | mixture or preparation that contains any quantity of the following |
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62 | 55 | | hallucinogenic substances, their salts, isomers and salts of |
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63 | 56 | | isomers, unless specifically excepted, when the ex istence of these |
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64 | 57 | | salts, isomers and salts of isomers is possible within the specific |
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65 | 58 | | chemical designation. |
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249 | 238 | | 24. N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-butenamide |
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250 | 239 | | (Crotonyl fentanyl); |
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251 | 240 | | 25. N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-2- |
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252 | 241 | | furancarboxamide (Furanyl fentanyl); |
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253 | 242 | | 26. N-phenyl-1-(2-phenylethyl)-4-piperidinamine (4-ANPP); |
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254 | 243 | | 27. N-(1-phenethylpiperidin-4-yl)-N- |
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255 | 244 | | phenylcyclopropanecarboxamide (Cyclopropyl fe ntanyl); or |
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256 | 245 | | 28. N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-butanamide |
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257 | 246 | | (Butyrl fentanyl). |
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258 | 247 | | C. Any material, compound, mixtur e, or preparation which |
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259 | 248 | | contains any quantity of the following h allucinogenic substances, |
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260 | 249 | | their salts, isomers, and salts of isomers, unless specifically |
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261 | 250 | | excepted, when the existence of these salts, isomers, and salts of |
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262 | 251 | | isomers is possible within the spec ific chemical designation: |
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263 | 252 | | 1. Methcathinone; |
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264 | 253 | | 2. 3, 4-methylenedioxy amphetamine; |
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265 | 254 | | 3. 3, 4-methylenedioxy methamphetamine; |
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266 | 255 | | 4. 5-methoxy-3, 4-methylenedioxy amphetami ne; |
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267 | 256 | | 5. 3, 4, 5-trimethoxy amphetamine; |
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268 | 257 | | 6. Bufotenine; |
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300 | 288 | | 11. Lysergic acid diethylamide; |
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301 | 289 | | 12. Marihuana; |
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302 | 290 | | 13. Mescaline; |
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303 | 291 | | 14. N-benzylpiperazine; |
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304 | 292 | | 15. N-ethyl-3-piperidyl benzilate; |
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305 | 293 | | 16. N-methyl-3-piperidyl benzilate; |
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306 | 294 | | 17. Psilocybin; |
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307 | 295 | | 18. Psilocyn; |
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308 | 296 | | 19. 2, 5 dimethoxyamphetamine; |
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309 | 297 | | 20. 4 Bromo-2, 5-dimethoxyamphetamine; |
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310 | 298 | | 21. 4 methoxyamphetam ine; |
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311 | 299 | | 22. Cyclohexamine; |
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312 | 300 | | 23. Salvia Divinorum; |
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313 | 301 | | 24. Salvinorin A; |
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314 | 302 | | 25. Thiophene Analog of Phencyclidine. Also known as: 1 -(1-(2- |
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315 | 303 | | thienyl) cyclohexyl) piperidine; 2-Thienyl Analog of Phencyclidine; |
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316 | 304 | | TPCP, TCP; |
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317 | 305 | | 26. Phencyclidine (PCP); |
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318 | 306 | | 27. Pyrrolidine Ana log for Phencyclidine. Also known as 1 -(1- |
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319 | 307 | | Phenylcyclohexyl) - Pyrrolidine, PCPy, PHP; |
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351 | 338 | | 32. 2,5-dimethoxy-4-nitroamphetamine; |
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352 | 339 | | 33. 2,5-dimethoxy-4-bromophenethylamine; |
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353 | 340 | | 34. 2,5-dimethoxy-4-chlorophenethylamine; |
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354 | 341 | | 35. 2,5-dimethoxy-4-iodoamphetamine; |
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355 | 342 | | 36. 2,5-dimethoxy-4-iodophenethylamine; |
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356 | 343 | | 37. 2,5-dimethoxy-4-methylphenethylamine; |
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357 | 344 | | 38. 2,5-dimethoxy-4-ethylphenethylamine; |
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358 | 345 | | 39. 2,5-dimethoxy-4-fluorophenethylamine; |
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359 | 346 | | 40. 2,5-dimethoxy-4-nitrophenethylamine; |
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360 | 347 | | 41. 2,5-dimethoxy-4-ethylthio-phenethylamine; |
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361 | 348 | | 42. 2,5-dimethoxy-4-isopropylthio-phenethylamine; |
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362 | 349 | | 43. 2,5-dimethoxy-4-propylthio-phenethylamine; |
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363 | 350 | | 44. 2,5-dimethoxy-4-cyclopropylmethylthio -phenethylamine; |
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364 | 351 | | 45. 2,5-dimethoxy-4-tert-butylthio-phenethylamine; |
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365 | 352 | | 46. 2,5-dimethoxy-4-(2-fluoroethylthio)-phenethylamine; |
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366 | 353 | | 47. 5-methoxy-N, N-dimethyltryptamine; |
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367 | 354 | | 48. N-methyltryptamine; |
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368 | 355 | | 49. A-ethyltryptamine; |
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369 | 356 | | 50. A-methyltryptamine; |
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370 | 357 | | 51. N, N-diethyltryptamine; |
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402 | 388 | | 56. 4-hydroxy-N, N-diisopropyltryptamine; |
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403 | 389 | | 57. 5-methoxy-N, N-diisopropyltryptamine; |
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404 | 390 | | 58. 4-hydroxy-N-isopropyl-N-methyltryptamine; |
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405 | 391 | | 59. 3,4-Methylenedioxymethcathinone (Methylone); |
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406 | 392 | | 60. 3,4-Methylenedioxypyrovalerone (MDPV); |
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407 | 393 | | 61. 4-Methylmethcathinone (Mephedrone); |
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408 | 394 | | 62. 4-methoxymethcathinone; |
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409 | 395 | | 63. 4-Fluoromethcathinone; |
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410 | 396 | | 64. 3-Fluoromethcathinone; |
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411 | 397 | | 65. 1-(8-bromobenzo 1,2-b;4,5-b’ difuran-4-yl)-2-aminopropane; |
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412 | 398 | | 66. 2,5-Dimethoxy-4-chloroamphetamine; |
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413 | 399 | | 67. 4-Methylethcathinone; |
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414 | 400 | | 68. Pyrovalerone; |
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415 | 401 | | 69. N,N-diallyl-5-methoxytryptamine; |
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416 | 402 | | 70. 3,4-Methylenedioxy-N-ethylcathinone (Ethylone); |
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417 | 403 | | 71. B-keto-N-Methylbenzodioxolylbutanamine (Butylone); |
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418 | 404 | | 72. B-keto-Methylbenzodioxolylpentanamine (Pentylone); |
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419 | 405 | | 73. Alpha-Pyrrolidinopentiophenone; |
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420 | 406 | | 74. 4-Fluoroamphetamine; |
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421 | 407 | | 75. Pentedrone; |
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453 | 438 | | 80. N,N-Dimethylamphetamine; |
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454 | 439 | | 81. 4-Fluoromethamphetamine; |
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455 | 440 | | 82. 4-Chloro-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine |
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456 | 441 | | (25C-NBOMe); |
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457 | 442 | | 83. 4-Iodo-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine |
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458 | 443 | | (25I-NBOMe); |
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459 | 444 | | 84. 4-Bromo-2,5-dimethoxy-N-(2-methoxybenzy)phenethylamine |
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460 | 445 | | (25B-NBOMe); |
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461 | 446 | | 85. 1-(4-Fluorophenyl)piperazine; |
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462 | 447 | | 86. Methoxetamine; |
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463 | 448 | | 87. 3,4-dichloro-N[2-dimethylamino)cyclohexyl] -N- |
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464 | 449 | | methylbenzamide; |
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465 | 450 | | 88. N-ethyl hexadrone; |
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466 | 451 | | 89. Isopropyl-U-47700; |
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467 | 452 | | 90. Para-fluorobutyrl fentanyl; |
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468 | 453 | | 91. Fluoro isobutryrl fentanyl; |
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469 | 454 | | 92. 3-Hydroxy Phencyclidine (PCP); or |
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470 | 455 | | 93. 3-methoxy Phencyclidine (PCP) ; |
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471 | 456 | | 94. Flualprazolam; or |
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472 | 457 | | 95. Flubromazolam. |
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504 | 488 | | 1. Fenethylline; |
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505 | 489 | | 2. Mecloqualone; |
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506 | 490 | | 3. N-ethylamphetamine; |
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507 | 491 | | 4. Methaqualone; |
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508 | 492 | | 5. Gamma-Hydroxybutyric Acid, also known a s GHB, gamma- |
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509 | 493 | | hydroxybutyrate, 4-hydroxybutyrate, 4-hydroxybutanoic acid, sodium |
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510 | 494 | | oxybate, and sodium oxybutyrate; |
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511 | 495 | | 6. Gamma-Butyrolactone (GBL) as packaged, marketed, |
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512 | 496 | | manufactured or promoted for human consumption, wi th the exception |
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513 | 497 | | of legitimate food addi tive and manufacturing purposes; |
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514 | 498 | | 7. Gamma Hydroxyvalerate (GHV) as packaged, marketed , or |
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515 | 499 | | manufactured for human consumption, with the exception of legitimate |
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516 | 500 | | food additive and manufacturing purposes; |
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517 | 501 | | 8. Gamma Valerolactone (GVL) as packaged, marketed , or |
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518 | 502 | | manufactured for human consumption, with the exception of legitimate |
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519 | 503 | | food additive and manufacturing purposes; |
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520 | 504 | | 9. 1,4 Butanediol (1,4 BD or BDO) as packaged, marketed, |
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521 | 505 | | manufactured, or promoted for human consumpti on with the exception |
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522 | 506 | | of legitimate manufacturing purposes; or |
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523 | 507 | | 10. N-ethylpentylone. |
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555 | 538 | | a. pesticides, |
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556 | 539 | | b. photochemical etching, |
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557 | 540 | | c. electrolytes of small batteries or capacitors, |
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558 | 541 | | d. viscosity modifiers in polyurethane, |
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559 | 542 | | e. surface etching of metal coated plastics, |
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560 | 543 | | f. organic paint disbursements for water soluble in ks, |
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561 | 544 | | g. pH regulators in the dyeing of wo ol and polyamide |
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562 | 545 | | fibers, |
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563 | 546 | | h. foundry chemistry as a catalyst during curing, |
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564 | 547 | | i. curing agents in many coating systems based on |
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565 | 548 | | urethanes and amides, |
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566 | 549 | | j. additives and flavoring agen ts in food, confectionary , |
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567 | 550 | | and beverage products, |
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568 | 551 | | k. synthetic fiber and cloth ing production, |
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569 | 552 | | l. tetrahydrofuran production, |
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570 | 553 | | m. gamma butyrolactone production, |
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571 | 554 | | n. polybutylene terephthalate resin production, |
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572 | 555 | | o. polyester raw materials for polyurethane elas tomers |
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573 | 556 | | and foams, |
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574 | 557 | | p. coating resin raw material, and |
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606 | 588 | | Gamma Valerolactone, or 1,4 Butanediol from being included as a |
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607 | 589 | | Schedule I controlled substance if such product is labeled, |
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608 | 590 | | marketed, manufactured and distributed for legitimate industrial use |
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609 | 591 | | in a manner that reduces or eliminates the likelihood of abuse. |
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610 | 592 | | 3. In making a determination regarding an industrial product, |
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611 | 593 | | the Director, after notice and hearing, shall consider the |
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612 | 594 | | following: |
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613 | 595 | | a. the history and current pattern of abuse, |
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614 | 596 | | b. the name and labeling of the product, |
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615 | 597 | | c. the intended manner of d istribution, advertising a nd |
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616 | 598 | | promotion of the product, and |
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617 | 599 | | d. other factors as may be relevant to and consistent |
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618 | 600 | | with the public health and safety. |
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619 | 601 | | 4. The hearing shall be held in accordance with the procedures |
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620 | 602 | | of the Administrative Procedures Act. |
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621 | 603 | | F. Any material, compound, mixt ure, or preparation, whether |
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622 | 604 | | produced directly or in directly from a substance of vegetable origin |
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623 | 605 | | or independently by means of chemical synthesis, or by a combination |
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624 | 606 | | of extraction and chemical synthesis, that contains any quantit y of |
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625 | 607 | | the following substan ces, or that contains any of their salts, |
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963 | 938 | | 146. AKB48 N-5-Fluorpentyl; |
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964 | 939 | | 147. AM1248; |
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965 | 940 | | 148. FUB-PB-22; |
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966 | 941 | | 149. ADB-FUBINACA; |
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967 | 942 | | 150. BB-22; |
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968 | 943 | | 151. 5-Fluoro PB-22; or |
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969 | 944 | | 152. 5-Fluoro AKB-48. |
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970 | 945 | | G. In addition to those substances listed in subsection F of |
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971 | 946 | | this section, unless specifically excepted or unless listed i n |
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972 | 947 | | another schedule, any material, compou nd, mixture, or preparation |
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973 | 948 | | which contains any quantity of a synthetic cannabinoid found to be |
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974 | 949 | | in any of the following chemical groups: |
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975 | 950 | | 1. Naphthoylindoles: a ny compound containing a 3-(1- |
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976 | 951 | | naphthoyl)indole structure with or without substitution at the |
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977 | 952 | | nitrogen atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, |
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978 | 953 | | alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1 - |
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979 | 954 | | (N-methyl-2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl- |
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980 | 955 | | 2-pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, |
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981 | 956 | | (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or |
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982 | 957 | | halophenyl group, whether or not further substituted on the indole |
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1013 | 987 | | a. 1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH- |
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1014 | 988 | | 200), |
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1015 | 989 | | b. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole (AM2201), |
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1016 | 990 | | c. 1-pentyl-3-(1-naphthoyl)indole (JWH-018), |
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1017 | 991 | | d. 1-butyl-3-(1-naphthoyl)indole (JWH -073), |
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1018 | 992 | | e. 1-pentyl-3-(4-methoxy-1-naphthoyl)indole (JWH-081), |
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1019 | 993 | | f. 1-propyl-2-methyl-3-(1-naphthoyl)indole (JWH-015), |
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1020 | 994 | | g. 1-hexyl-3-(1-naphthoyl)indole (JWH -019), |
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1021 | 995 | | h. 1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH -122), |
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1022 | 996 | | i. 1-pentyl-3-(4-ethyl-1-naphthoyl)indole (JWH -210), |
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1023 | 997 | | j. 1-pentyl-3-(4-chloro-1-naphthoyl)indole (JWH-398), |
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1024 | 998 | | k. 1-pentyl-2-methyl-3-(1-naphthoyl)indole (JWH-007), |
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1025 | 999 | | l. 1-pentyl-3-(7-methoxy-1-naphthoyl)indole (JWH -164), |
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1026 | 1000 | | m. 1-pentyl-2-methyl-3-(4-methoxy-1-naphthoyl)indole |
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1027 | 1001 | | (JWH-098), |
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1028 | 1002 | | n. 1-pentyl-3-(4-fluoro-1-naphthoyl)indole (JWH-412), |
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1029 | 1003 | | o. 1-[1-(N-methyl-2-piperidinyl)methyl]-3-(1- |
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1030 | 1004 | | naphthoyl)indole (AM-1220), |
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1031 | 1005 | | p. 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole |
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1032 | 1006 | | (MAM-2201), or |
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1033 | 1007 | | q. 1-(4-cyanobutyl)-3-(1-naphthoyl)indole (AM -2232); |
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1064 | 1037 | | alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl , halobenzyl, 1- |
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1065 | 1038 | | (N-methyl-2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1 -(N-methyl- |
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1066 | 1039 | | 2-pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, |
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1067 | 1040 | | (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl , or |
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1068 | 1041 | | halophenyl group, whether or not further substituted on the indole |
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1069 | 1042 | | ring to any extent, and wh ether or not substituted on the naphthyl |
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1070 | 1043 | | ring to any extent. Naphthylmethylindoles include, but are not |
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1071 | 1044 | | limited to, (1-pentylindol-3-yl)(1-naphthyl)methane (JWH -175); |
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1072 | 1045 | | 3. Naphthoylpyrroles: any compound containing a 3 -(1- |
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1073 | 1046 | | naphthoyl)pyrrole structure with o r without substitution at the |
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1074 | 1047 | | nitrogen atom of the pyrrole ring by an alkyl, haloalkyl, |
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1075 | 1048 | | cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, |
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1076 | 1049 | | halobenzyl, 1-(N-methyl-2-piperidinyl)methyl, 2 -(4- |
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1077 | 1050 | | morpholinyl)ethyl, 1-(N-methyl-2-pyrrolidinyl)methyl, 1-(N-methyl-3- |
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1078 | 1051 | | morpholinyl)methyl, (tetr ahydropyran-4-yl)methyl, 1-methylazepanyl, |
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1079 | 1052 | | phenyl, or halophenyl group, whether or not further substituted on |
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1080 | 1053 | | the pyrrole ring to any extent, and whether or not substituted on |
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1081 | 1054 | | the naphthyl group to any extent. Napht hoylpyrroles include, but |
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1082 | 1055 | | are not limited to: |
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1083 | 1056 | | a. 1-hexyl-2-phenyl-4-(1-naphthoyl)pyrrole (JWH-147), |
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1115 | 1087 | | 4. Naphthylideneindenes: an y compound containing a 1-(1- |
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1116 | 1088 | | naphthylmethylene)indene structure with or without substitution at |
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1117 | 1089 | | the 3-position of the indene ring by an alkyl, haloalkyl, |
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1118 | 1090 | | cyanoalkyl, alkenyl, cyc loalkylmethyl, cycloalkylethyl, benzyl , |
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1119 | 1091 | | halobenzyl, 1-(N-methyl-2-piperidinyl)methyl, 2-(4- |
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1120 | 1092 | | morpholinyl)ethyl, 1-(N-methyl-2-pyrrolidinyl)methyl, 1 -(N-methyl-3- |
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1121 | 1093 | | morpholinyl)methyl, (tetrahydropyran -4-yl)methyl, 1-methylazepanyl, |
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1122 | 1094 | | phenyl, or halophenyl group, whether or not further substituted on |
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1123 | 1095 | | the indene group to any extent, and whet her or not substituted on |
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1124 | 1096 | | the naphthyl group to any extent. Naphthylmethylindenes include, |
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1125 | 1097 | | but are not limited to, (1 -[(3-pentyl)-1H-inden-1- |
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1126 | 1098 | | ylidene)methyl]naphthalene (JWH -176); |
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1127 | 1099 | | 5. Phenylacetylindoles: any compoun d containing a 3- |
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1128 | 1100 | | phenylacetylindole stru cture with or without substitution at the |
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1129 | 1101 | | nitrogen atom of the indole ring by alkyl, haloalkyl, cyanoalkyl, |
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1130 | 1102 | | alkenyl, cycloalkylme thyl, cycloalkylethyl, benzyl, halobenzyl, 1 - |
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1131 | 1103 | | (N-methyl-2-piperidinyl)methyl, 2 -(4-morpholinyl)ethyl, 1-(N-methyl- |
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1132 | 1104 | | 2-pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, |
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1133 | 1105 | | (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl , or |
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1134 | 1106 | | halophenyl group, whether or not further substituted on the indole |
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1166 | 1137 | | b. 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole |
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1167 | 1138 | | (RCS-8), |
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1168 | 1139 | | c. 1-pentyl-3-(2-chlorophenylacetyl)indole (JWH-203), |
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1169 | 1140 | | d. 1-pentyl-3-(2-methylphenylacetyl)indole (JWH-251), |
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1170 | 1141 | | e. 1-pentyl-3-(4-methoxyphenylacetyl)indole (JWH -201), or |
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1171 | 1142 | | f. 1-pentyl-3-(3-methoxyphenylacetyl)indole ( JWH-302); |
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1172 | 1143 | | 6. Cyclohexylphenols: any compound con taining a 2-(3- |
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1173 | 1144 | | hydroxycyclohexyl)pheno l structure with or without substitution at |
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1174 | 1145 | | the 5-position of the phenolic ring by an alkyl, haloalkyl, |
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1175 | 1146 | | cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, |
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1176 | 1147 | | halobenzyl, 1-(N-methyl-2-piperidinyl)methyl, 2 -(4- |
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1177 | 1148 | | morpholinyl)ethyl, 1 -(N-methyl-2-pyrrolidinyl)methyl, 1-(N-methyl-3- |
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1178 | 1149 | | morpholinyl)methyl, (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, |
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1179 | 1150 | | phenyl, or halophenyl group, and whether or not further substituted |
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1180 | 1151 | | on the cyclohexyl ring to any extent. Cyclohexylp henols include, |
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1181 | 1152 | | but are not limited to : |
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1182 | 1153 | | a. 5-(1,1-dimethylheptyl)-2-[(1R,3S)-3- |
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1183 | 1154 | | hydroxycyclohexyl]-phenol (CP-47,497), |
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1216 | 1186 | | 7. Benzoylindoles: any compound containing a 3-(benzoyl)indole |
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1217 | 1187 | | structure with or without substitution at the nitrogen atom of the |
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1218 | 1188 | | indole ring by an alkyl, haloalkyl, cyanoalkyl, al kenyl, |
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1219 | 1189 | | cycloalkylmethyl, cycloalkyleth yl, benzyl, halobenzyl, 1-(N-methyl- |
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1220 | 1190 | | 2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl-2- |
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1221 | 1191 | | pyrrolidinyl)methyl, 1 -(N-methyl-3- morpholinyl)methyl, |
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1222 | 1192 | | (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl , or |
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1223 | 1193 | | halophenyl group, whether or not further subs tituted on the indole |
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1224 | 1194 | | ring to any extent, and whether or not substituted on the phenyl |
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1225 | 1195 | | group to any extent. Benzoylindoles include, but are not limited |
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1226 | 1196 | | to: |
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1227 | 1197 | | a. 1-pentyl-3-(4-methoxybenzoyl)indole (RCS -4), |
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1228 | 1198 | | b. 1-[2-(4-morpholinyl)ethyl]-2-methyl-3-(4- |
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1229 | 1199 | | methoxybenzoyl)indole (Pravadoline or WIN 48, 0 98), |
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1230 | 1200 | | c. 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole (AM-694), |
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1231 | 1201 | | d. 1-pentyl-3-(2-iodobenzoyl)indole (AM -679), or |
---|
1232 | 1202 | | e. 1-[1-(N-methyl-2-piperidinyl)methyl]-3-(2- |
---|
1233 | 1203 | | iodobenzoyl)indole (AM -2233); |
---|
| 1204 | + | 8. Cyclopropoylindoles: Any co mpound containing a 3- |
---|
| 1205 | + | (cyclopropoyl)indole structure with substitution at the nitrogen |
---|
| 1206 | + | atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, |
---|
| 1207 | + | cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1 -(N-methyl- |
---|
| 1208 | + | 2-piperidinyl)methyl, 2 -(4-morpholinyl)ethyl, 1-(N-methyl-2- |
---|
| 1209 | + | pyrrolidinyl)methyl, 1-(N-methyl-3- morpholinyl)methyl, |
---|
1261 | | - | 8. Cyclopropoylindoles: Any compound containing a 3 - |
---|
1262 | | - | (cyclopropoyl)indole structure with substitution at the nitrogen |
---|
1263 | | - | atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, |
---|
1264 | | - | cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1 -(N-methyl- |
---|
1265 | | - | 2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1 -(N-methyl-2- |
---|
1266 | | - | pyrrolidinyl)methyl, 1 -(N-methyl-3- morpholinyl)methyl, |
---|
1267 | 1236 | | (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl , or |
---|
1268 | 1237 | | halophenyl group, whether or not further substituted in the indole |
---|
1269 | 1238 | | ring to any extent and whether or not substitut ed in the |
---|
1270 | 1239 | | cyclopropoyl ring to any exten t. Cyclopropoylindoles include, but |
---|
1271 | 1240 | | are not limited to: |
---|
1272 | 1241 | | a. 1-pentyl-3-(2,2,3,3-tetramethylcyclopropoyl)indole |
---|
1273 | 1242 | | (UR-144), |
---|
1274 | 1243 | | b. 1-(5-chloropentyl)-3-(2,2,3,3- |
---|
1275 | 1244 | | tetramethylcyclopropoyl) indole (5Cl-UR-144), or |
---|
1276 | 1245 | | c. 1-(5-fluoropentyl)-3-(2,2,3,3- |
---|
1277 | 1246 | | tetramethylcyclopropo yl)indole (XLR11); |
---|
1278 | 1247 | | 9. Indole Amides: Any compound containing a 1H-Indole-3- |
---|
1279 | 1248 | | carboxamide structure with or without substitution at the nitrogen |
---|
1280 | 1249 | | atom of the indole ring by an alky l, haloalkyl, cyanoalkyl, alkenyl, |
---|
1281 | 1250 | | cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1-(N-methyl- |
---|
1282 | 1251 | | 2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1 -(N-methyl-2- |
---|
1283 | 1252 | | pyrrolidinyl)methyl, 1 -(N-methyl-3- morpholinyl)methyl, |
---|
1284 | 1253 | | (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or |
---|
| 1254 | + | halophenyl group, whether or not substituted at the carbo xamide |
---|
| 1255 | + | group by an adamantyl, naphthyl, phenyl, benzyl, quinolinyl, |
---|
| 1256 | + | cycloalkyl, 1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl- |
---|
| 1257 | + | 1-oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- |
---|
| 1258 | + | dimethyl-1-oxobutan-2-yl or pyrrole group, and whether or not |
---|
| 1259 | + | further substituted in the indole, adamantyl, naphthyl, phenyl, |
---|
1312 | | - | halophenyl group, whether or not substituted at the carboxamide |
---|
1313 | | - | group by an adamantyl, naphthyl, phenyl, benzyl, quinolinyl, |
---|
1314 | | - | cycloalkyl, 1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl- |
---|
1315 | | - | 1-oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- |
---|
1316 | | - | dimethyl-1-oxobutan-2-yl or pyrrole group, and whether or not |
---|
1317 | | - | further substituted in the indole, adamantyl, naphthyl, phenyl, |
---|
1318 | 1286 | | pyrrole, quninolinyl , or cycloalkyl rings to any extent. Indole |
---|
1319 | 1287 | | Amides include, but are not limited to: |
---|
1320 | 1288 | | a. N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide |
---|
1321 | 1289 | | (2NE1), |
---|
1322 | 1290 | | b. N-(1-adamantyl)-1-(5-fluoropentyl-1H-indole-3- |
---|
1323 | 1291 | | carboxamide (STS-135), |
---|
1324 | 1292 | | c. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H- |
---|
1325 | 1293 | | indole-3-carboxamide (ADBICA), |
---|
1326 | 1294 | | d. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5- |
---|
1327 | 1295 | | fluoropentyl)-1H-indole-3-carboxamide (5F-ADBICA), |
---|
1328 | 1296 | | e. N-(naphthalen-1-yl)-1-pentyl-1H-indole-3-carboxamide |
---|
1329 | 1297 | | (NNE1), |
---|
1330 | 1298 | | f. 1-(5-fluoropentyl)-N-(naphthalene-1-yl)-1H-indole-3- |
---|
1331 | 1299 | | carboxamide (5F-NNE1), |
---|
1332 | 1300 | | g. N-benzyl-1-pentyl-1H-indole-3-carboxamide (SDB-006), |
---|
1333 | 1301 | | or |
---|
1334 | 1302 | | h. N-benzyl-1-(5-fluoropentyl)-1H-indole-3-carboxamide |
---|
1335 | 1303 | | (5F-SDB-006); |
---|
| 1304 | + | 10. Indole Esters: Any compound containing a 1H-Indole-3- |
---|
| 1305 | + | carboxylate structure with or without substitution at the nitrogen |
---|
| 1306 | + | atom of the indole ring by an alkyl, haloalkyl, cyanoa lkyl, alkenyl, |
---|
| 1307 | + | cycloalkylmethyl, cyclo alkylethyl, benzyl, halobenzyl, 1 -(N-methyl- |
---|
| 1308 | + | 2-piperidinyl)methyl, 2-(4-morpholinyl)ethyl, 1-(N-methyl-2- |
---|
| 1309 | + | pyrrolidinyl)methyl, 1 -(N-methyl-3-morpholinyl)methyl, |
---|
1363 | | - | 10. Indole Esters: Any compound containing a 1H -Indole-3- |
---|
1364 | | - | carboxylate structure with or without substitution at the nitrogen |
---|
1365 | | - | atom of the indole ring by an alkyl, haloalkyl, cyanoalkyl, alkenyl, |
---|
1366 | | - | cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1 -(N-methyl- |
---|
1367 | | - | 2-piperidinyl)methyl, 2 -(4-morpholinyl)ethyl, 1 -(N-methyl-2- |
---|
1368 | | - | pyrrolidinyl)methyl, 1 -(N-methyl-3-morpholinyl)methyl, |
---|
1369 | 1336 | | (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl , or |
---|
1370 | 1337 | | halophenyl group, whether or not subst ituted at the carboxylate |
---|
1371 | 1338 | | group by an adamantyl, naphthyl, phenyl, benzyl, quinolinyl, |
---|
1372 | 1339 | | cycloalkyl,1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl-1- |
---|
1373 | 1340 | | oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- |
---|
1374 | 1341 | | dimethyl-1-oxobutan-2-yl or pyrrole group, and whether or not |
---|
1375 | 1342 | | further substituted in the indole, adamantyl, naphthyl, phenyl, |
---|
1376 | 1343 | | pyrrole, quinolinyl, or cycloalkyl rings to any extent. Indole |
---|
1377 | 1344 | | Esters include, but are not limited to: |
---|
1378 | 1345 | | a. quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate (PB- |
---|
1379 | 1346 | | 22), |
---|
1380 | 1347 | | b. quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3- |
---|
1381 | 1348 | | carboxylate (5F-PB-22), |
---|
1382 | 1349 | | c. quinolin-8-yl 1-(cyclohexylmethyl)-1H-indole-3- |
---|
1383 | 1350 | | carboxylate (BB-22), |
---|
1384 | 1351 | | d. naphthalen-1-yl 1-(4-fluorobenzyl)-1H-indole-3- |
---|
1385 | 1352 | | carboxylate (FDU-PB-22), or |
---|
| 1353 | + | e. naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3- |
---|
| 1354 | + | carboxylate (NM2201); |
---|
| 1355 | + | 11. Adamantanoylindoles: Any compound containing an |
---|
| 1356 | + | adamantanyl-(1H-indol-3-yl)methanone structure with or without |
---|
| 1357 | + | substitution at the nitrogen atom of the indole ring by an alkyl, |
---|
| 1358 | + | haloalkyl, cyanoalkyl, alkenyl, cycloal kylmethyl, cycloalkylethyl, |
---|
| 1359 | + | benzyl, halobenzyl, 1-(N-methyl-2-piperidinyl)methyl, 2-(4- |
---|
1413 | | - | e. naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3- |
---|
1414 | | - | carboxylate (NM2201); |
---|
1415 | | - | 11. Adamantanoylindoles: Any compound containing an |
---|
1416 | | - | adamantanyl-(1H-indol-3-yl)methanone structure with or without |
---|
1417 | | - | substitution at the nitrogen atom of the indole ring by an alkyl, |
---|
1418 | | - | haloalkyl, cyanoalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, |
---|
1419 | | - | benzyl, halobenzyl, 1 -(N-methyl-2-piperidinyl)methyl, 2 -(4- |
---|
1420 | 1386 | | morpholinyl)ethyl, 1-(N-methyl-2-pyrrolidinyl)methyl, 1 -(N-methyl-3- |
---|
1421 | 1387 | | morpholinyl)methyl, (tetrahydropyran -4-yl)methyl, 1-methylazepanyl, |
---|
1422 | 1388 | | phenyl, or halophenyl group, whe ther or not further substituted in |
---|
1423 | 1389 | | the indole ring to any extent and whether or not substituted in the |
---|
1424 | 1390 | | adamantyl ring to any extent. Adamantanoylindoles include, but are |
---|
1425 | 1391 | | not limited to: |
---|
1426 | 1392 | | a. adamantan-1-yl[1-[(1-methyl-2-piperidinyl)methyl]-1H- |
---|
1427 | 1393 | | indol-3-yl]methanone (AM1248), or |
---|
1428 | 1394 | | b. adamantan-1-yl-(1-pentyl-1H-indol-3-yl)methanone (AB- |
---|
1429 | 1395 | | 001); |
---|
1430 | 1396 | | 12. Carbazole Ketone: Any compound containing (9H -carbazole-3- |
---|
1431 | 1397 | | yl) methanone structure with or without substitution at the nitrogen |
---|
1432 | 1398 | | atom of the carbazole ring by an alkyl, haloalkyl, cyanoalkyl, |
---|
1433 | 1399 | | alkenyl, cycloalkylmethyl, cycloalkylethyl, benzyl, halobenzyl, 1- |
---|
1434 | 1400 | | (N-methyl-2-piperidinyl)methyl, 2 -(4-morpholinyl)ethyl, 1 -(N-methyl- |
---|
1435 | 1401 | | 2-pyrrolidinyl)methyl, 1 -(N-methyl-3-morpholinyl)methyl, |
---|
1436 | 1402 | | (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or |
---|
| 1403 | + | halophenyl group, with substitution at the carbon of the methanone |
---|
| 1404 | + | group by an adamantyl, naphthyl, phenyl, benzyl, quinolinyl, |
---|
| 1405 | + | cycloalkyl, 1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl- |
---|
| 1406 | + | 1-oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- |
---|
| 1407 | + | dimethyl-1-oxobutan-2-yl or pyrrole group, and whether or not |
---|
| 1408 | + | further substituted at the carbazole, adamantyl, naphthyl, phenyl, |
---|
| 1409 | + | pyrrole, quinolinyl, or cycloalkyl rings to any extent. Carbazole |
---|
1464 | | - | halophenyl group, with substitution at the carbon of the methanone |
---|
1465 | | - | group by an adamantyl, naphthyl, phenyl, benzyl, quinolinyl, |
---|
1466 | | - | cycloalkyl, 1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl- |
---|
1467 | | - | 1-oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- |
---|
1468 | | - | dimethyl-1-oxobutan-2-yl or pyrrole group, and whether or not |
---|
1469 | | - | further substituted at the carbazole, adamantyl, naphthyl, phenyl, |
---|
1470 | | - | pyrrole, quinolinyl, or cycloalkyl rings to any extent. Carbazole |
---|
1471 | 1436 | | Ketones include, but are not limited to, naphthalen-1-yl(9-pentyl- |
---|
1472 | 1437 | | 9H-carbazol-3-yl)methanone (EG-018); |
---|
1473 | 1438 | | 13. Benzimidazole Ketone: Any compound containing |
---|
1474 | 1439 | | (benzimidazole-2-yl) methanone structure with or without |
---|
1475 | 1440 | | substitution at either nitrogen atom of the benzimidazole ring by an |
---|
1476 | 1441 | | alkyl, haloalkyl, cyanoalkyl, alkenyl, cycloalkylmet hyl, |
---|
1477 | 1442 | | cycloalkylethyl, benzyl, halobenzyl, 1-(N-methyl-2- |
---|
1478 | 1443 | | piperidinyl)methyl, 2 -(4-morpholinyl)ethyl, 1 -(N-methyl-2- |
---|
1479 | 1444 | | pyrrolidinyl)methyl, 1 -(N-methyl-3-morpholinyl)methyl, |
---|
1480 | 1445 | | (tetrahydropyran-4-yl)methyl, 1-methylazepanyl, phenyl, or |
---|
1481 | 1446 | | halophenyl group, with subst itution at the carbon of the methanone |
---|
1482 | 1447 | | group by an adamantyl, naphthyl, phenyl, benzyl, quinolinyl, |
---|
1483 | 1448 | | cycloalkyl, 1-amino-3-methyl-1-oxobutan-2-yl, 1-amino-3,3-dimethyl- |
---|
1484 | 1449 | | 1-oxobutan-2-yl, 1-methoxy-3-methyl-1-oxobutan-2-yl, 1-methoxy-3,3- |
---|
1485 | 1450 | | dimethyl-1-oxobutan-2-yl or pyrrole group, and whether or not |
---|
1486 | 1451 | | further substituted in the benzimidazole, adamantyl, naphthyl, |
---|
| 1452 | + | phenyl, pyrrole, quinolinyl , or cycloalkyl rings to any extent. |
---|
| 1453 | + | Benzimidazole Ketones include, but are not limit ed to: |
---|
| 1454 | + | a. naphthalen-1-yl(1-pentyl-1H-benzo[d]imidazol-2- |
---|
| 1455 | + | l)methanone (JWH-018 benzimidazole analog), or |
---|
| 1456 | + | b. (1-(5-fluoropentyl)-1H-benzo[d]imidazol-2- |
---|
| 1457 | + | yl)(naphthalen-1-yl)methanone (FUBIMINA); and |
---|
1514 | | - | phenyl, pyrrole, quinolinyl , or cycloalkyl rings to any extent. |
---|
1515 | | - | Benzimidazole Ketones include, but are not limited to: |
---|
1516 | | - | a. naphthalen-1-yl(1-pentyl-1H-benzo[d]imidazol-2- |
---|
1517 | | - | l)methanone (JWH-018 benzimidazole analog), or |
---|
1518 | | - | b. (1-(5-fluoropentyl)-1H-benzo[d]imidazol-2- |
---|
1519 | | - | yl)(naphthalen-1-yl)methanone (FUBIMINA); and |
---|